The crossed phrenic phenomenon

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The crossed phrenic phenomenon

The cervical spine is the most common site of traumatic vertebral column injuries. Respiratory insufficiency constitutes a significant proportion of the morbidity burden and is the most common cause of mortality in these patients. In seeking to enhance our capacity to treat specifically the respiratory dysfunction following spinal cord injury, investigators have studied the "crossed phrenic phe...

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Significance of the Crossed Phrenic Phenomenon’ L. JEROME LEWIS AND JOHN M, BROOKHART

T HE THOROUGH and oft-quoted experiments of Porter (I) were designed to determine the presence or absence of crossing connections between the descending inspiratory reticulospinal fibers of one side and the phrenic motor nuclei of the opposite side. In demonstrating the existence of such connections, Porter repeated an observation which had been made previously (z-4) and formulated an hypothesi...

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Contribution of the spontaneous crossed-phrenic phenomenon to inspiratory tidal volume in spontaneously breathing rats.

Spinal cord hemisection at C2 (C2HS) severs bulbospinal inputs to ipsilateral phrenic motoneurons causing transient hemidiaphragm paralysis. The spontaneous crossed-phrenic phenomenon (sCPP) describes the spontaneous recovery of ipsilateral phrenic bursting following C2HS. We reasoned that the immediate (next breath) changes in tidal volume (V(T)) induced by ipsilateral phrenicotomy during spon...

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The Crossed Respiratory Impulses to the Phrenic

Langendorff (1887) and Girard (1890) observed contractions of one half of the diaphragm in rabbits and dogs after an ipsilateral semisection of the spinal cord above C3 and severance of the contralateral phrenic nerve. Schiff (1894) and Porter (1895) showed that the crossing of the respiratory impulses did not occur until the phrenic was cut on the opposite side. Porter further demonstrated tha...

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Significance of the Crossed Phrenic Phenomenon’ L. JEROME LEWIS AND JOHN M, BROOKHART

T HE THOROUGH and oft-quoted experiments of Porter (I) were designed to determine the presence or absence of crossing connections between the descending inspiratory reticulospinal fibers of one side and the phrenic motor nuclei of the opposite side. In demonstrating the existence of such connections, Porter repeated an observation which had been made previously (z-4) and formulated an hypothesi...

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ژورنال

عنوان ژورنال: Neural Regeneration Research

سال: 2017

ISSN: 1673-5374

DOI: 10.4103/1673-5374.208539